Background. Digital Rectal Examination (DRE) is one of the earliest, easiest, and most cost-effective tools in clinical medicine. Its viability in contemporary practice has come under scrutiny due to advancements in imaging. This article revisits its clinical applications in light of the recent literature. Methods. A search of PubMed and Google Scholar was conducted using various MeSH subheadings related to digital rectal examination, and on the basis of available literature, the versatility of the DRE was examined, specifically focusing on its essential role in the initial detection and assessment of prostate disorders, anorectal pathology, and gastrointestinal emergencies. Conclusion. Recent trends show a decrease in the routine performance of DRE, often due to reliance on advanced diagnostics, evolving screening guidelines, and deficiencies in training. DRE is not obsolete but rather a timeless clinical art that can provide immediate and often life-saving diagnostic information cost-effectively, particularly when modern diagnostic facilities are not available. There is a need to improve the training of DRE and use it as per the evidence.
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